Research Into CF Complications

Complications of cystic fibrosis affect everyone with the disease, regardless of their mutation. The Cystic Fibrosis Foundation is supporting research into CF complications, such as infections, inflammation, excessive mucus, and gastrointestinal issues, to develop better treatments and improve outcomes for people with CF.

What You Need To Know

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Infection Research Initiative

The Cystic Fibrosis Foundation has committed at least $100 million from 2019-2023 to the Infection Research Initiative, a comprehensive effort to improve the detection, diagnosis, treatment, and outcomes of CF-related infections. Since the launch in 2018, the Foundation has awarded over $58 million to infection research.

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  1. Explainer

    Infections

    People with cystic fibrosis are prone to infections because of the thick, sticky mucus that clogs their airways. The Cystic Fibrosis Foundation is funding research to help fight these infections.

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  2. Explainer

    Inflammation

    Chronic inflammation in people with cystic fibrosis causes damage to lung tissue that can eventually lead to respiratory failure. Researchers are trying to discover ways to dampen the exaggerated immune response that causes chronic inflammation without affecting the body’s natural defenses against infection.

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  3. Explainer

    Mucus

    People with cystic fibrosis have thick, sticky mucus that blocks passages in their lungs, making it difficult for them to breathe and predisposing them to infections. New drugs are under development that will help break up and hydrate mucus in the lungs to make it easier to clear.

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  1. Explainer

    Gastrointestinal Issues and Cystic Fibrosis-Related Diabetes

    People with cystic fibrosis can experience complications in the pancreas, liver, and intestines that can lead to malnutrition, constipation, liver disease, CF-related diabetes, and other digestive issues -- including abdominal pain and poor appetite.

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Find a Clinical Trial

Help us blaze a trail to better treatments and a cure for CF. Find a clinical trial that may be right for you.

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